Neuropixels V1#

Authors:

Jonathan P. Newman

Version:

1

IO:

Frame Source, Register Access

ONIX ID:

11

ONIX Hubs:

Neuropixels-1.0 Headstage

Description#

The Neuropixels V1 Device acquires data from Neuropixels V1 probes.

Register Programming#

Managed Registers#

Managed register access is provided at offset 0x8000.

Managed Registers#

Address

Name

Access

Time of Effect

POR Value

Reset Action

Description

0x8000

ENABLE

R/W

On Reset

Implementation dependent, see hub documentation

None

The LSB is used to enable or disable the device data stream:

  • 0x0: data output disabled

  • 0x1: data output enabled

Unmanaged Registers#

Direct, unmanaged read and write access is provided to the Neuropixels V1 registers, which are reproduced here for clarity. The time of effect of changes to these registers are defined by the probe. Complete documentation is available through IMEC.

Unmanaged Registers#

Address

Name

Access

Time of Effect

POR Value

Reset Action

Description

0x00

OP_MODE

R/W

See IMEC docs

“00000000”

None

Operation mode register.

0x01

REC_MOD

R/W

See IMEC docs

“11000000”

None

Recording flags register.

0x02

CAL_MOD

R/W

See IMEC docs

“00000000”

None

Calibration flags register.

0x03

TEST_CONFIG1

R/W

See IMEC docs

“00000000”

None

Test configuration register 1.

0x04

TEST_CONFIG2

R/W

See IMEC docs

“00000000”

None

Test configuration register 2.

0x05

TEST_CONFIG3

R/W

See IMEC docs

“00000000”

None

Test configuration register 3.

0x06

TEST_CONFIG4

R/W

See IMEC docs

“00000000”

None

Test configuration register 4.

0x07

TEST_CONFIG5

R/W

See IMEC docs

“00000000”

None

Test configuration register 5.

0x08

STATUS

R/W

See IMEC docs

“00000000”

None

Shift register error status.

0x09

SYNC

R/W

See IMEC docs

“00000000”

None

Sync code for delineating data frames.

0x0a

SR_CHAIN5

R/W

See IMEC docs

“00000000”

None

Shift register chain 5.

0x0b

SR_CHAIN4

R/W

See IMEC docs

“00000000”

None

Shift register chain 4.

0x0c

SR_CHAIN3

R/W

See IMEC docs

“00000000”

None

Shift register chain 3.

0x0d

SR_CHAIN2

R/W

See IMEC docs

“00000000”

None

Shift register chain 2.

0x0e

SR_CHAIN1

R/W

See IMEC docs

“00000000”

None

Shift register chain 1.

0x0f

SR_LENGTH2

R/W

See IMEC docs

“00000000”

None

Shift register byte read length 2.

0x10

SR_LENGTH1

R/W

See IMEC docs

“00000000”

None

Shift register byte read length 1.

0x11

SOFT_RESET

R/W

See IMEC docs

“00000000”

None

Software issued synchronous reset.

Device To Host Data Frames#

Each frame transmitted to the host consists of a single Neuropixels V1 “Super Frame” containing all 384 AP channels and a single set of 32 LFP channels. Twelve of Super Frames are required to construct a single “Ultra Frame” which contains 12 samples from each the 384 AP channels and a single sample from each of the 384 LFP channels.

Each ONIX frame is organized as follows:

Here, LFP and AP “Frames” are not actually 32-bits words but full, 32-ADC sample blocks. Each one of these blocks is organized as follows:

Definitions for each of these fields are as follows:

Sync Type

Fixed word indicating the frame type - 207: Normal frame. Frame contains AP data. - 816: Super frame start. Frame contains LFP data.

ADC Voltage

Unsigned integer. Only the 10 LSBs are valid.

Frame Counter

A looping 24-bit frame counter produced by the probe to detect dropped frames and to ensure proper reset sequence that results in a count of 0 at the start of transmission.

Host To Device Data Frames#

This device does not accept input frames. All write attempts will fail with an error.